Community of Practice on AI for HTA activities

Established by the HTAi Global Policy Forum (GPF) in July 2025 with the aim to interconnect members of the GPF, HTAi Interest Groups, and other subject experts to advance the understanding and appropriate use of AI for HTA activities in a safe, responsible, and equitable way.

Community of Practice on AI for HTA activities

Established in July 2025 (currently active)

Leaders

Seye Abogunrin (Roche)
Timothy Reason (Estima Scientific)

Coordination Group
  • Richard Charter (HTAi MDIG)
  • Rachel Fleurence (NIH & ISPOR)
  • Pall Jonsson (NICE)
  • Sven Klijn (BMS)
  • Bill Malcolm (BMS)
  • Elena Petelos (HTAi RWE&AI IG)
  • Lizzie Shanahan (Sanofi)
  • Dan Singh (CDA-AMC)
  • Rebecca Trowman (HTAi GPF)
  • Eva Turk (HTAi Board)
  • Kristof Vanfraechem (Data For Patients)
  • Rosa Maria Vivanco (AQuAS)
  • Siw Waffenschmidt (IQWIG)
  • Tina Wang (CIRS)
Members
  • Rossana Rivas (RedETSA)
  • Gabriel Rickemberg (RedETSA)
  • Silvina Benchetrit (RedETSA)

Overview

The HTAi Community of Practice (CoP) on Artificial Intelligence (AI) for Health Technology Assessment (HTA) activities was established by the Global Policy Forum members to continue the dialogue on this topic. Generative AI for HTA activities was the main focus and was defined as “a branch of AI that learns patterns from large datasets and uses that understanding to create brand-new, original content, such as text, images, or code, in response to user prompts.”

Applications in the following areas were originally identified: Systematic literature review and evidence synthesis; Real-World Evidence (RWE); Health economic modeling; Product dossier preparation.

It is acknowledged that the field evolves at extremely fast pace and the scope of the CoP may evolve to include emerging AI paradigms.

Purpose

The CoP aims to enable continuous knowledge exchange, collaboration, and co-production of tools, guidance, and frameworks on the use of AI for HTA activities. The tasks and activity lines are identified and prioritized by its Coordination Group. The following topics represent the current scope of the CoP: transparency, traceability, accountability, autonomy, decision-making, use-case repository, methodological guidance, validation frameworks, governance and legal issues, risk stratification, training and capacity building, futurist perspectives in HTA transformation.

Deliverables

  • Knowledge products: e.g., methodological guidance, validation protocols, case-studies repository, tutorials.
  • Content to events: e.g., webinars, conferences, workshops.
  • Peer learning sessions led by internal or external experts.
  • Policy briefs, white papers, journal articles, and conference materials to inform HTA policy and advocacy.
  • Feedback on the use of AI tools for HTA activities.