Lifecycle Approaches in the HTA Task Force

Overview

While the concept of evaluating technologies across their lifecycle is not new, with discussion in both regulatory and HTA contexts, the HTA community is increasingly discussing how to apply lifecycle approaches in HTA. Lifecycle HTA has been proposed as a way to manage evidentiary uncertainty, address changes in the evidence base, the design of the technology, or the clinical pathway, and support iterative decision making. However, there is no consensus definition of the term “LC-HTA” or how this term relates to similar concepts such as Health Technology Reassessment, “Living HTA” or “Health Technology Management”.  

Purpose

To develop a position statement, including developing a definition of lifecycle HTA (LC-HTA), identifying where LC-HTA approaches could add value to HTA bodies and HTA-related stakeholders, developing an LC-HTA framework and high-level guidance \for how to operationalize LC-HTA. The Task Force was composed of a geographically diverse group of GPF members and people representing HTA bodies, academia, technology developers (pharmaceuticals and devices), and nonprofit organizations.

Deliverables

Lifecycle HTA: promising applications and a framework for implementation. An HTAi Global Policy Forum Task Force report. 
Pichler FB, Boysen M, Mittmann N, et al.
International Journal of Technology Assessment in Health Care. 2024;40(1):e50.

An operationalization framework for lifecycle health technology assessment: a Health Technology Assessment International Global Policy Forum Task Force report. 
Pichler FB, Boysen M, Mittmann N, et al.
International Journal of Technology Assessment in Health Care. 2024;40(1):e45.